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X-WR-CALNAME;VALUE=TEXT:UMCES Events
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DTSTART:20201101T020000
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UID:calendar.21124.field_date_time.0@www.umces.edu
DTSTAMP:20260405T222732Z
CREATED:20200512T131318Z
DESCRIPTION:July 8\, 2020 3:00pm to 4:00pm    \n    \n      \n\n\n    \n\n 
              \nInstitute of Marine & Environmental Technology\n      \n\n
 \n\n\n  \n\n    \n\n              \n\n\n      \n  \n\n    \n\n            
   \n\n\nTitle: Microbial natural products in drug discovery – Stories from
  fungi and bacteria and their chemistry\n\n\n\nSpeaker: Dr. Sandra Loesgen
  (Associate Professor of Chemistry\, University of Florida)\n\n\n\nAbstrac
 t: 'Many microorganisms produce secondary metabolites that are believed to
  have critical roles in intra- and inter-species communication\, competiti
 on for resources\, or defense of a symbiotic partner. Despite the importan
 ce of these metabolites\, it is estimated that only a small fraction of mi
 crobial secondary metabolites has been identified\, and a much smaller fra
 ction of identified secondary metabolites have well-established ecological
  functions. The secondary metabolites of microorganisms often exhibit inhe
 rent biological activities\, and many have are serving as clincailly appro
 ved drugs\, examples are antibiotic penicillin from Penicillium fungi and 
 the chemotherapeutic doxorubicin from Streptomyces bacteria.\n\n\n\n\nIn t
 his seminar\, I will give an overview of the research in the Loesgen Lab o
 n fungal and bacterial metabolites from both terrestrial and marine habita
 ts. In our drug discovery program\, we pursue new compounds with antibioti
 c\, antiviral\, and anticancer activity. I will give examples of our scree
 ning and gene activation approaches and will present the latest news towar
 ds the mode-of-action studies of the melanoma selective metabolite mensaca
 rcin.\n\n\n\nHost: Dr. Som Chatterjee\n\n\n\nIf you would like to attend v
 irtually\, please email imetdirectorsoffice@umces.edu
DTSTART;TZID=America/New_York:20200708T150000
DTEND;TZID=America/New_York:20200708T160000
LAST-MODIFIED:20200611T131513Z
SUMMARY:Virtual IMET Seminar: Dr. Sandra Loesgen (Associate Professor\, Uni
 versity of Florida)
URL;TYPE=URI:https://www.umces.edu/events/virtual-imet-seminar-dr-sandra-lo
 esgen-associate-professor-university-of-florida
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