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X-WR-CALNAME;VALUE=TEXT:UMCES Events
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DTSTART:20201101T020000
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DTSTART:20210314T020000
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UID:calendar.22414.field_date_time.0@www.umces.edu
DTSTAMP:20260416T203055Z
CREATED:20210210T170805Z
DESCRIPTION:March 24\, 2021 3:00pm to 4:00pm    \n    \n      \n\n\n    \n
 \n              \nInstitute of Marine & Environmental Technology\n      \n
 \n\n\n\n  \n\n    \n\n              \n\n\n      \n  \n\n    \n\n          
     \n\n\nTitle: 'Zebrafish GnRH neurons communicate synaptically to contr
 ol their own migration'\n\n\n\nSpeaker: Dr. Matan Golan (Researcher\, Isra
 eli Agricultural Research Organization\, The Volcani Center)\n\n\n\nAbstra
 ct: Reproduction in all vertebrates is controlled by a small group of hypo
 thalamic neurons that secrete Gonadotropin-Releasing Hormone (GnRH). These
  neurons are born in the nose\, outside of the central nervous system\, an
 d migrate into the brain during embryonic development. Despite the great i
 mportance of these cells\, studying their migration is challenging because
  in mammals the process takes place inside the mother's uterus. To study t
 he migration of GnRH neurons in vivo\, we used zebrafish since their small
  and transparent embryos develop externally\, making it possible to follow
  the migration and activity of the cells as it would occur naturally\, in 
 a whole and live organism. Using this approach\, we revealed that\, contra
 ry to what we thought\, GnRH neurons do not migrate alone. Instead\, the c
 ells create an isolated\, spontaneously active circuit that is internally 
 wired through monosynaptic glutamatergic synapses into which newborn GnRH 
 neurons integrate before entering the brain. This initial phase of integra
 tion drives a phenotypic switch\, which is essential for GnRH neurons to p
 roperly migrate toward their hypothalamic destination. We therefore propos
 e an updated model for GnRH neuronal migration\, critical for vertebrate r
 eproduction and species survival\, in which the population controls the mi
 gration of individual units.\n\n\n\nHost: Dr. Nilli Zmora\n\n\n\nIf you wo
 uld like to attend virtually\, please email imetdirectorsoffice@umces.edu
DTSTART;TZID=America/New_York:20210324T150000
DTEND;TZID=America/New_York:20210324T160000
LAST-MODIFIED:20210318T124704Z
SUMMARY:Virtual IMET Seminar: Dr. Matan Golan (Researcher\, Israeli Agricul
 tural Research Organization
URL;TYPE=URI:https://www.umces.edu/events/virtual-imet-seminar-dr-matan-gol
 an-researcher-israeli-agricultural-research-organization
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